Posted in Psychology & Medicine

Symptom Reporting

Some people always complain of symptoms, claiming that they are sick, while some people never seem to complain even if they have a whole list of symptoms. Why is there a difference in symptom reporting between people? For example, women are more likely to recognise symptoms and report them compared to men. This is because men are generally under the social pressure of needing to appear strong and healthy, so they become stoic and less sensitive to pain and disease. Women are usually more sensitive to internal bodily changes and worry more about their health.

According to a psychological theory called the competition for cues hypothesis, there are two signals that compete for attention when we recognise symptoms. The first is bodily changes, i.e. internal cues, while the other is external stimuli from what happens around us. Awareness of symptoms follows a ratio between these two signals: if there is a strong internal cue such as severe pain, we notice symptoms more quickly, while if there are many distractions, we may not notice the symptom. For example, according to a study people can run faster when listening to music and running through a forest with plenty to see. This is because music and the scenery distract the runner from internal cues. As we can only process a certain amount of information at a given moment, the more distractions there are the less sensitive we become to signals from inside our body.

Another factor that affects symptom reporting is illness labelling. The more information we have about a disease, the more we search for those symptoms. For example, if you yawn or scratch yourself, people around you will do the same. This is because they see you yawning and subconsciously believe that they should yawn too. This can be a powerful effect, as seen in mass hysteria. This strange phenomenon occurs when a person observes a sick person and their brain believes they are sick too, beginning to show symptoms despite being healthy. A similar example is seen in medical student disease, where medical students, with their extensive knowledge of diseases, match their own symptoms to symptom lists of rare diseases. For example, they might think that their high blood pressure is due to a phaeochromocytoma or renal artery stenosis, rather than just hypertension.

However, the opposite can occur where people fail to notice important symptoms and suffer serious consequences as a result. For instance, not all cases of heart attacks (myocardial infarction) cause unconsciousness and a patient may believe they are fine when only chest pain occurs. Failure to get treated as soon as possible at a hospital may result in ventricular fibrillation, leading to sudden death.

Posted in Psychology & Medicine

Sudden Death

Unlike diseases such as tuberculosis or cancer, some disease processes are known to kill a human being within an hour of onset. Other than the obvious causes such as decapitation, massive bleeding or any other trauma-related injuries, these diseases tend to be cardiac or respiratory in origin.

A common example is coronary artery disease, where the blood vessel providing blood to an area of the heart becomes completely blocked by stenosis (narrowing, often by atherosclerosis) or a clot. This results in immediate ischaemia (lack of oxygen) to heart muscles, which causes cell death. This produces scar tissue which disrupts the electrical activity of the heart, which may lead to a condition called ventricular fibrillation where the heart beats in an uncontrolled, erratic manner. When in VF, the heart effectively becomes useless as it cannot coordinate proper pumping function. Blood circulation stops and the patient goes in to multiple organ failure (the brain goes first) within a very short time. Although it can kill within a short time, early identification and treatment may be able to prevent VF from occurring and save the patient’s life. If VF does occur, it is crucial to begin CPR or use a defibrillator if available.

VF can also occur in other situations. For example, there is a genetic condition called long QT syndrome which predisposes the patient to spontaneous arrhythmias (electrical abnormalities in the heart). Even becoming too excited can sometimes set off a VF in some LQTS patients, thus they require an implantable cardioverter-defibrillator (ICD) to shock their heart back in to normal rhythm every time they develop an arrhythmia.

Some other causes of sudden death include: aortic dissection (tearing of the aorta that may cause massive internal bleeding), pulmonary embolism (a clot obstructs blood flow in the lung, stopping circulation), commotio cordis (a blow to the heart at a certain moment in the heart rhythm triggers VF), ruptured brain aneurysm (ballooning of an artery in the brain), anaphylaxis (severe allergic reaction that cuts off airflow to the lungs) and poisoning (various mechanisms, mainly related to disrupting cellular function).

Death can strike swiftly, even from within your body.

Posted in Psychology & Medicine

Broken Heart Syndrome

Countless novels and films depict a character, heartbroken from the loss of a loved one or due to a break-up, suddenly clutch their chest and collapse. Although this may seem like a dramatic plot device, it is actually possible to die from stress.

The condition, colloquially termed broken heart syndrome for obvious reasons, is known as takotsubo cardiomyopathy or stress-induced cardiomyopathy. As the name suggests, the heart suddenly goes into congestive heart failure after sudden emotional stress. In simpler words, the heart’s ability to pump blood is sharply reduced due to muscle weakness and blood is not circulated properly. This causes blood to dam up and cause symptoms such as chest pain, breathlessness, fluid overload and much more.

The characteristics of this disease is that the heart temporarily enlarges so that the tip (apex) bulges out while the function of the base (upper part of the heart) is normal. The muscles in the apex is thinned while the base has hypertrophied and thickened. This gives the appearance of a thin pocket with a thick entrance, thus giving the name takotsubo cardiomyopathy, which means “octopus trap” in Japanese.
Given the patient survives the initial heart failure, their condition improves over the course of two months. The patient may also need psychiatric help or antidepressants and sedatives to ease the stress that led to the heart failure. 

As the presentation is very similar to a normal myocardial infarction (“heart attack”), the diagnosis may be difficult. The cause has not been identified yet, but researchers believe it to be due to a combination of blood vessel spasms disrupting blood supply to the heart and high levels of catecholamines. As catecholamines (adrenaline/noradrenaline) are released in great quantities in times of stress, this theory has some plausibility. A similar thing happens when patients with heart problems are exposed to significant levels of fear – their heart goes into overdrive and develop cardiac arrest due to an exacerbation of their condition.

The concept of dying from intense emotions such as anger and stress is found in almost every culture, where a person collapses and falls deathly ill after shocking news or a particularly stressful experience. But modern medicine has only just begun to understand the scientific reasoning behind this strange phenomenon.

It has also been noted that takotsubo cardiomyopathy tends to affect post-menopausal women, especially widows. Interestingly, most of these patients are not considered “at risk” for a heart attack and generally healthy. 
Thus, stress alone can be enough to “break” someone’s heart and cause sudden death.

(Sourcehttp://sndr.deviantart.com/art/Broken-Heart-7445432?q=boost%3Apopular%20broken%20heart&qo=0)