Tag: disease

Posted in Psychology & Medicine

Superbug

Posted on by Jinavie

Frequently on the media, the word “superbug” is used as if it were the new Black Death or the coming apocalypse. What is a superbug and why is it so feared?
Superbug is the colloquial nickname for drug-resistant bacteria. For example, one of the most famous superbugs is MRSA (methicillin-resistant Staphylococcus aureus). This strain S. aureus, a common bacteria found on skin and inside the nose, is resistant to a powerful antibiotic called methicillin and thus very hard to treat. Unfortunately, MRSA is most commonly contracted in hospital settings as patients are vulnerable to infections (e.g. after surgery) and hospitals are perfect breeding grounds for superbugs.

The cause of a “normal” bacteria turning into a superbug is due to the incorrect use of antibiotics. When antibiotics are used, they wipe out a significant portion of the bacterial population but fail to kill all of them in the first attack. The surviving bacteria are the more adapted ones that are able to withstand the harsh environment for a little longer. If the patient stops taking the antibiotics and the bacteria remains, these “drug-resistant” bacteria multiply to create a second infection that is resistant to the drug that was used previously. In fact, this is a classic example of natural selection in motion, except that the environmental change is man-made.
This is the reason why doctors are reluctant to prescribe antibiotics for diseases such as the common cold or viral diseases, as the risk of developing superbugs is greater than the benefit (which is zero in viral diseases as they do nothing) of the treatment. It is also why a course of antibiotics must be finished even if the patient is feeling well, so that even the surviving bacteria are eventually killed.

To show the potential risk of superbugs, the case of VRSA can be taken into consideration. When MRSA was first discovered, doctors found it very difficult to treat but luckily they had a secret weapon – vancomycin, one of the most powerful antibiotics known to mankind. However, they soon found that S. aureus and natural selection easily overcame this through a new strain called VRSA – vancomycin-resistant S. aureus. Here was a bacteria that could overcome the greatest weapon man had against bacteria, all because people were taking more antibiotics than needed and not taking the full course prescribed.

Thus, one of the growing problems of modern medicine is the development of new drugs so that we can make a comeback in the arms race against bacteria.

Posted in Psychology & Medicine

Gait

Posted on by Jinavie

In medicine, a person’s way of walking is termed gait. By analysing a person’s gait, a trained professional can gain insight into what pathologies the person may be suffering from. For example, just from the way the patient limps, the doctor may discover that the patient has an incurable degenerative brain disease.

The most common gait abnormality is the antalgic gait, or limping due to pain. Most people would have experienced the difficulty of walking with a sprained or broken ankle, muscle ache or knee problems. This is easy to spot as the patient quickly switches to the other feet when leaning on the affected leg due to the pain. Therefore, the side that stays on the ground less than the other is the affected leg.

Sometimes, you can see a person “waddling” along as they swing from one side to the other. This may be a waddling gait, also known as Trendelenburg’s gait, caused by a weakness in the hip muscles that support the pelvic girdle, either due to muscle or nerve damage. As the patient cannot support their weight on the affected side, their pelvis tilts towards the opposite side. To avoid falling over, the patient lurches their body towards the other side, causing them to waddle. Looking at the tilt and lurch gives insight into what side is affected.
Another rather common gait is the steppage gait, where the person lifts one leg higher than the other, while their foot drags on the ground. This is caused by nerve damage leading to the loss of ability to lift the foot up (termed foot drop).

As the brain controls the motor system, damage to the brain also leads to motor dysfunction. A common example is a stroke.
If the stroke damages a significant part of the motor cortex, the patient suffers from hemiparesis/hemiplegia, or weakness/paralysis of one half of the body. This causes the limbs on the affected side to stiffen, as seen by an extended leg pointing inwards and retracted arm. The patient has to swing the affected leg around while they walk as they cannot flex the hip, known as a hemiplegic gait.
If the cerebellum is damaged, balancing becomes an issue. This causes the patient to suffer from ataxia, where they cannot coordinate their movements and are prone to toppling over. These patients tend to sway violently from side to side as they try to walk in a straight line.

Lastly, degenerative brain diseases can also affect gait. There are two main examples.
In Parkinson’s disease, the patient suffers from what is called hypokinesia and bradykinesia – reduced and slow movement. This leads to a shuffling gait where the patient walks slowly by shuffling their feet in small steps. They are also stooped over and are often seen with a pill-rolling tremor of their hands – a cardinal symptom of the disease.
In Huntington’s chorea, the opposite (hyperkinesia) occurs. This causes flailing as the muscles contract in an uncoordinated manner, including both the arms and legs. Ergo, their gait is quite jerky and interrupted by bouts of flailing, termed choreiform gait, but their balance is fine so walking in a straight line is still possible.

Knowledge of these disorders may help one appreciate the suffering a patient walking along the street has to undergo everyday of their life.

(Video demonstrations: http://stanford25.wordpress.com/gait-abnormalities/)

Posted in Life & Happiness

Blindness

Posted on by Jinavie

Cataracts, glaucoma, macular degeneration, corneal disease, diabetes, trauma, optic nerve disease; myopia, hypermetropia, astigmatism, colour blindness…
There are many causes and types of blindness, but by far the most powerful, debilitating and dangerous blindness is prejudice – the blindness to what is deep to the surface.

This disease affects 100% of the adult population and causes a severe impairment in judgement, leading the patient to make wrong assumptions. Much like colour blindness, prejudice robs the world of colour, transforming it into black-or-white. The patient’s visual acuity falls dramatically, not being able to see the beautiful scenery of the human soul, and instead seeing a distorted, superficial image.

Despite the devastating effects of the disease and extreme prevalence, the treatment is simple. Just as you would treat someone who claims that “the room is too dark” – take off your sunglasses and see the world for what it truly is.

(Source: http://www.deviantart.com/download/193661196/aph__color_by_lolitamyangel-d37atxo.jpg)

Posted in Psychology & Medicine

Sexsomnia

Posted on by Jinavie

There are many interesting medical facts regarding sleep, but there are strange pathologies that stand out even more from them.
Sometimes, cases resembling sleepwalking are reported, where the patient unconsciously has sexual intercourse with someone else. After waking up, the patient has no recollection of the event, and thus may face a very awkward situation the following morning.

Sexsomnia, or sleep sex, is a rare sleep disorder; to be more specific, it is a type of NREM parasomnia (performing complex actions while asleep). This disorder is quite different from REM sleep disorder, as no dreaming occurs during NREM sleep. Therefore, the sexual behaviour is not due to the influence of an erotic dream, but rather the primitive brain functions acting on basic instincts, as higher brain functions are shut down during NREM sleep. According to reports, sexsomniacs act almost lucidly during episodes.
As it was discovered quite recently, less than 15 years ago, it is under heavy research. However, due to patients feeling too ashamed of the disease or not remembering the events, the number of reported cases is low.

This disease is not directly harmful to the patient, but it can be very problematic socially. It ruins relationships and may even lead to rape. But as the law defines rape as “a conscious act”, sexsomnia is often used as a defence in trials. It is important to note that it occurs in both men and women. Within relationships, the general complaint is not that of rape, but rather exhaustion.
Interestingly, as the primitive brain is not being controlled during the episodes, sleep sex is known to be more vigorous than normal sex. Due to this, patients and their partners often exhibit carpet burns.

Posted in Psychology & Medicine

Madness

Posted on by Jinavie

“As mad as a hatter” – this is a well-known English idiom, particularly famous after Lewis Carroll created the Mad Hatter character in his work Alice in Wonderland. However, what is less known is the fact that this idiom is based on actual events.

In the 18th and 19th centuries, hatters used mercury to treat felt (traditionally made from rabbit fur or the more luxurious beaver fur). Unfortunately, mercury is a highly toxic heavy metal, which causes severe damage in the human body. In the case of mercury poisoning (also known as Minamata disease or the Mad Hatter disease), it infiltrates neurons to cause severe neurological symptoms. For example, it can impair vision and hearing, cause paresthesia (pins and needles), anxiety, depression, tremors and hallucinations. The famous physicist, Isaac Newton, also suffered from Mad Hatter disease.

Another mad character from Alice in Wonderland is the March Hare. As one may deduce from his name, he is modelled after a normal hare. The reason why the March Hare is mad is that March is around the time when rabbits enter their mating season, and male hares are in heat. They then have only one thing in mind: sex. 

Maybe, as the Cheshire Cat explains, “we’re all mad down here”.

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Posted in Psychology & Medicine

Alice In Wonderland Syndrome

Posted on by Jinavie

There is a disease called Alice in Wonderland Syndrome. This causes patients to suffer massive migraines, while suffering visual hallucinations that alter their perception of what they see.
For example, they see objects as bigger or smaller than what they actually are, or even see them as upside-down. Because of this, people who have experienced this syndrome say that it was like living in a fairy tale. There is no known cure, but it is often temporary and will one day disappear like magic.

When you fall in love, the other person’s weaknesses seem smaller, their strengths seem bigger, and sometimes they turn your world upside-down. So is love like living in a fairy tale, or like suffering a disease?.

(Source: http://fc07.deviantart.net/fs71/i/2010/120/e/9/Alice_in_Wonderland_by_UlaFish.jpg)

Posted in Science & Nature

Fainting Goat

Posted on by Jinavie

There is a very interesting breed of goats called the Fainting Goat. These goats suffer a genetic condition called myotonia congenita, which produces fascinating yet hilarious situations. When startled by the sudden presence of another animal or even a loud noise, these goats all suddenly freeze and fall to one side. This phenomenon can occur even while running, which causes the goats to crash into the ground, lying on their backs with their legs straight up. This can even occur from the excitement of seeing food and starting to run towards it.

The reason for this peculiar phenomenon is that myotonia congenita damages systems that allow muscles to relax, causing it to become easily excited. Ergo, when a goat is startled, its muscles tense reflexively, causing it to contract suddenly while taking longer to relax. This results in the goat becoming paralysed and falling. Young goats tend to be helpless when this occurs, but more experienced goats prop their legs apart quickly or lean against something to prevent falling (they can even be seen hopping on their stiff legs). These “fainting spells” are painless.

Although this kind of trait is often removed by natural selection (for example, in nature these goats would freeze when they meet a predator, and then proceed to be eaten), humans have bred these goats specifically to save their trait. In old times, these goats were used as “sacrifices” so that they would get eaten first when wolves struck, but nowadays they are bred in certain farms for no particular use. 
Myotonia congenita also affects other animals such as cats, and there are many people in the world affected by this condition too.