Posted in Psychology & Medicine

Overpopulation

In 1972, John B. Calhoun designed a very specific mice cage called Universe 25, also known as the Mortality-Inhibiting Environment for Mice. Universe 25 was designed as a practical utopia for mice. It was constantly replenished with food and water, each wall had an intricate grid of nesting boxes connected by mesh tunnels and stairwells (like an apartment) and the cage was cleaned periodically. There were no predators, the temperature was set at a comfortable level and all mice resident were disease-free. In all ways, Universe 25 was an idyllic home for the mice.

Calhoun’s aim of this experiment was the same as the countless experiments before Universe 25: to see the effects of abundance on a population, and the consequences of that. Biologically speaking, a population only grows to the point that the environment can sustain it and then plateaus. So if the environment is completely abundant, the population will grow and grow without limitations (other than space). Thus, Calhoun’s main focus was overpopulation in societies. What did he find?

At the start of the experiment, four breeding pairs of mice were introduced to Universe 25. They began reproducing after 104 days of familiarisation and the population increased exponentially. The mice flourished in the prosperous environment. Around day 315, population growth slowed. By this stage, the mice population had grown to over 600, which made Universe 25 very crowded. Although there were still plenty of resources, the problem of overpopulation still remained. As the population grew and space became limited, male mice found it too difficult to defend their territory and eventually gave up doing so. The mice began losing their ability to form social bonds and these mice (“failures”) began congregating at the centre of the cage. This group of mice gave up on all normal social behaviour, leading to constant violence. The violence soon spread throughout the cage, with the mice society descending into chaos. The females, stressed and confused by the violence, attacked and cannibalised their own young, after which they retreated to the highest nest boxes where they isolated themselves. Certain males (termed “the beautiful ones” by Calhoun) did not show violence or any interest in females, choosing only to eat, sleep and groom themselves, wrapped in narcissistic introspection. Because of these two isolated groups, procreation slumped and population growth slowed. Elsewhere, in the “inner city” group at the middle of the cage, cannibalism, pansexualism and violence became common. The entire society had collapsed.

On day 560, the population ceased to grow at a peak population of 2200. After this, the number of pregnancies dwindled to nothing and no young survived past infancy. Adult mice were also affected, with mortality rates skyrocketing at all ages and increased rates of diseases. It was clear that the population was headed towards extinction. Even after the population dwindled down to a much more sustainable number, the mice were incapable of (or chose not to) reproducing to regenerate the population. Not only did mice society die, but the mice themselves met a grim fate as well.

This result was repeated in all of Calhoun’s experiments, conclusively showing that overpopulation leads to the demise of a society. Calhoun described this as “crowding into the behavioural sink”. He explained that the mice served as a warning to what human societies are headed towards if we do not solve the problem of overpopulation. We can already see the effect overpopulation has on societies. It is a known fact that people living in the inner areas of a city are more prone to poverty, crime, violence and a lower quality of life. However, Calhoun was not a nihilist. Instead of saying “humanity is doomed”, he explored different ways of resolving the problem. The most effective idea he came up with was space colonisation.

Posted in Psychology & Medicine

Kuru

European explorers who visited the island of Papua New Guinea in the 1950’s noticed that the Fore tribe suffered from a strange disease. The patient would initially have headaches, joint pains and tremors. They then show signs of weakness and are unable to stand.  The shaking of limbs, a classic symptom of the disease, becomes progressively worse as the disease progresses (“kuru” is a Fore word for “to shake”). In the late stages, the patient shows other neurological symptoms such as uncontrollable laughter and emotional instability. By this point, their tremors and ataxia (lack of coordination) is so severe that they cannot sit without support. They may also suffer from inability to speak or swallow, become unresponsive to their surroundings, develop ulcers on the skin and become incontinent (cannot hold urine/faeces). Within 3 months to 2 years after the symptoms develop, the patient dies.

Kuru is exclusive to the Fore tribe and medical researchers were puzzled by the nature of this disease. It is incurable and takes more than 10 years to develop (from the time of infection). In 1961, Dr Michael Alpers discovered that kuru was spread due to a certain cultural behaviour within the tribe – cannibalism. The Fore tribe had a tradition of eating the corpse of a deceased tribe member at the funeral as to return their life force back in to the tribe. Of course, this involved the consumption of the brain as well.

It was discovered that kuru is caused by a strange pathogen known as a prion. Prions are misfolded pieces of proteins that cause disease by converting the body’s proteins into “wrong” proteins. These new prions then convert more proteins until the body is filled with deposits of such proteins. Prions mainly affect the brain and cause spongiform encephalopathy – meaning that the brain becomes sponge-like and full of holes. The most famous example of prion disease is mad cow disease.

After colonists took over Papua New Guinea, cannibalism was banned and kuru faded away. This was proof that cannibalism was what spread the prion from one victim to another. It was also discovered that women and children had a higher incidence as men would have priority in choosing what part of the body to eat first. As with lions, the men always chose muscles first and women and children would often finish the organs such as the brain. As prions are indestructible, it cannot be treated, cured or prevented (other than not eating brains). It also means that it transmits perfectly from a dead patient to an unsuspecting victim who is feasting on the infected brain.

A disease that causes the brain to disintegrate, causing limb shaking and inability to walk, spread by the ingestion of brains. Is it possible that zombies are caused by eating brains and not the other way around?

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